Its building began in 1278 and the church was part of the convent of the Humiliati, a congregation dedicated to evangelical perfection and poverty. In 1310, the Majesty by Giotto, which is now in the Uffizi, was placed on the high altar. Other fourteenth-century works are housed in the sacristy. During the following century the church acquired, thanks to bequests, works by artists such as Botticelli and Ghirlandaio. In the mid - sixteenth century, the church and convent were transferred to the Franciscans by Cosimo I de' Medici. The facade was completed at the beginning of the seventeenth century according to a design by Matteo Righetti.
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